An san wannan Covid-19 yana ƙara haɗarin ciwon zuciya, bugun jini, da Doguwa Covid amma abin da ba a sani ba shi ne ko lalacewar ta faru ne saboda kwayar cutar tana cutar da ƙwayar zuciya da kanta, ko kuma saboda tsarin tsarin kumburi wanda aka fara ta hanyar rigakafi na jiki ga kwayar cutar. A cikin wani sabon binciken, masu bincike sun gano cewa kamuwa da cuta ta SARS-CoV-2 ya kara yawan adadin macrophages na zuciya kuma ya sa su canza daga aikin su na yau da kullun don zama masu kumburi. Macrophages na zuciya mai kumburi yana lalata da zuciya da sauran jikin. Har ila yau, masu binciken sun gano cewa toshe martanin rigakafi tare da antibody mai hana ruwa a cikin samfurin dabba ya dakatar da kwararar cututtukan zuciya. macrophages da kuma kiyaye aikin zuciya wanda ke nuna wannan tsarin yana da damar warkewa.
An san cewa COVID-19 yana ƙara haɗarin bugun zuciya, bugun jini, da Dogon COVID. Fiye da kashi 50% na mutanen da suka sami COVID-19 suna fuskantar wani kumburi ko lahani ga zuciya. Abin da ba a sani ba shi ne ko lalacewar ta faru ne saboda kwayar cutar tana cutar da ƙwayar zuciya da kanta, ko kuma saboda kumburin tsarin da garkuwar jiki ke haifar da cutar.
Wani sabon bincike ya ba da haske kan alaƙa tsakanin mummunan rauni na huhu a cikin COVID-19 mai tsanani da kumburin da zai iya haifar da rikice-rikice na zuciya. Binciken ya mayar da hankali kan ƙwayoyin rigakafi da aka sani da macrophages na zuciya, wanda yawanci yana yin muhimmiyar rawa wajen kiyaye lafiyar nama amma ya zama mai kumburi don amsawa ga rauni kamar ciwon zuciya ko ciwon zuciya.
Masu binciken sun yi nazarin samfuran ƙwayar zuciya daga marasa lafiya 21 waɗanda suka mutu daga SARS-CoV-2 mai alaƙa da matsanancin damuwa na numfashi (ARDS) kuma sun kwatanta su da samfuran daga marasa lafiya 33 waɗanda suka mutu daga abubuwan da ba COVID-19 ba. Don bin abin da ya faru da macrophages bayan kamuwa da cuta, masu binciken kuma sun kamu da beraye da SARS-CoV-2.
An gano cewa kamuwa da cutar ta SARS-CoV-2 ta ƙara adadin macrophages na zuciya a cikin mutane da beraye. Har ila yau ciwon ya sa macrophages na zuciya ya canza daga aikin su na yau da kullum don zama mai kumburi. Macrophages masu kumburi suna lalata zuciya da sauran jikin.
An tsara wani bincike a cikin beraye don gwada ko amsar da suka lura ta faru ne saboda SARS-CoV-2 tana cutar da zuciya kai tsaye, ko kuma saboda kamuwa da cutar SARS-CoV-2 a cikin huhu ya yi tsanani sosai don sa macrophages na zuciya ya zama mai kumburi. Wannan binciken ya kwaikwayi alamun kumburin huhu, amma ba tare da kasancewar ainihin kwayar cutar ba. An gano cewa ko da babu kwayar cuta, berayen sun nuna martanin rigakafin da ya isa ya samar da canjin macrophage na zuciya iri ɗaya wanda aka lura duka a cikin marasa lafiyar da suka mutu daga COVID-19 da berayen da suka kamu da cutar ta SARS-CoV-2. .
Kwayar cutar ta SARS-CoV-2 tana haifar da lahani kai tsaye a kan ƙwayar huhu. Bayan a Covid kamuwa da cuta, baya ga lalacewar kai tsaye ta kwayar cutar, tsarin rigakafi na iya lalata wasu gabobin ta hanyar haifar da kumburi mai ƙarfi a cikin jiki.
Abin sha'awa, an kuma gano cewa toshe martanin rigakafi tare da antibody neutralizing a cikin mice ya dakatar da kwararar macrophages na zuciya mai kumburi da kiyaye aikin zuciya. Wannan yana nuna cewa wannan hanya (wato hana kumburi na iya rage rikice-rikice) yana da damar warkewa idan an same shi lafiya kuma yana da inganci a gwaji na asibiti.
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References:
- NIH. Sabunta labarai - Mummunan kamuwa da cutar huhu yayin COVID-19 na iya haifar da lahani ga zuciya. An buga 20 Maris 2024. Akwai a https://www.nih.gov/news-events/news-releases/severe-lung-infection-during-covid-19-can-cause-damage-heart
- Grun J., et al 2024. Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cardiomyopathy tana haifar da Ciwon Jiki Ta hanyar Kashe Amsoshi masu kumburi a cikin Zuciya. Zagayawa. 2024; 0. An buga asali 20 Maris 2024. DOI: https://doi.org/10.1161/CIRCULATIONAHA.123.066433
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