COVID-19: JN.1 ƙaramin juzu'i yana da mafi girman watsawa da ƙarfin tserewa na rigakafi 

Maye gurbi (S: L455S) shine babban maye gurbi na JN.1 wanda ke daɗa haɓaka ƙarfin gujewa na rigakafi wanda ke ba shi damar gujewa kamuwa da ƙwayoyin cuta na Class 1 yadda ya kamata. Wani bincike yana goyan bayan amfani da sabbin rigakafin COVID-19 tare da furotin mai kauri don ƙara kare jama'a.  

A karuwa a Covid-19 An samu rahoton bullar cutar a sassa da dama na duniya. Wani sabo sub-variant JN.1 (BA.2.86.1.1) wanda ya samo asali da sauri daga BA.2.86 bambancin kwanan nan yana haifar da damuwa.  

JN.1 (BA.2.86.1.1) sãɓãwar launukansa yana da ƙarin maye gurbi (S: L455S) idan aka kwatanta da precursor BA.2.86. Wannan shine babban maye gurbi na JN.1 wanda ke haɓaka iyawar sa na ƙauracewa samar da shi yadda ya kamata ya guje wa nau'in rigakafi na Class 1 yadda ya kamata. JN.1 kuma yana ɗauke da maye gurbi guda uku a cikin furotin da ba na S ba. Gabaɗaya, JN.1 ya ƙara haɓakawa da ƙarfin tserewa na rigakafi^1,2.  

Alurar rigakafin COVID-19 sun yi nisa tun lokacin bala'i kuma an sabunta su tare da la'akari da furotin mai kauri don fuskantar ƙalubalen da sabbin bambance-bambancen ke haifarwa.  

Wani bincike na baya-bayan nan ya nuna cewa an sabunta monovalent maganin mRNA (XBB.1.5 MV) yana da tasiri wajen haɓaka ƙwayoyin rigakafin ƙwayoyin cuta-neutralization mai mahimmanci akan yawancin ƙananan bambance-bambance ciki har da JN.1. Wannan binciken yana goyan bayan amfani da sabbin rigakafin COVID-19 tare da furotin mai kauri don ƙara kare jama'a³.  

Idan juzu'in JN.1  ya ba da ƙarin haɗari ga lafiyar jama'a dangane da sauran bambance-bambancen da ke yawo a halin yanzu, CDC ta ce babu wata shaida.⁴.  

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References:  

1. Yan S., et al 2023. Saurin juyin halitta na SARS-CoV-2 BA.2.86 zuwa JN.1 a ƙarƙashin matsanancin matsin lamba na rigakafi. Preprint bioRxiv. An buga Nuwamba 17, 2023. DOI: https://doi.org/10.1101/2023.11.13.566860  
2. Kaku Y., et al 2023. Virological halaye na SARS-CoV-2 JN.1 bambancin. Preprint bioRxiv. An buga Disamba 09, 2023. DOI: https://doi.org/10.1101/2023.12.08.570782  
3. Wang Q. et al 2023. XBB.1.5 monovalent mRNA mai haɓaka maganin rigakafi yana haifar da tsauraran ƙwayoyin rigakafi daga bambance-bambancen SARS-CoV-2 masu tasowa. Preprint bioRxiv. An buga Disamba 06, 2023. DOI: https://doi.org/10.1101/2023.11.26.568730  
4. Cibiyar Kula da Cututtuka. Sabuntawa akan SARS-CoV-2 Variant JN.1 CDC Na Bibiya. Akwai a https://www.cdc.gov/respiratory-viruses/whats-new/SARS-CoV-2-variant-JN.1.html   

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